هل تقصد : what is metallothionein?
Metallothionein - an overview | ScienceDirect Topics
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Metallothionein (MT) is a small metal-binding protein with 61–68 amino acid residues, which include 20 cysteines, that is bound to a total of seven equivalents ...
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What is the function of metallothionein?
Metallothioneins (MTs) are small cysteine-rich proteins that play important roles in metal homeostasis and protection against heavy metal toxicity, DNA damage, and oxidative stress.
What are the benefits of metallothionein?
Metallothionein, by virtue of its metal ion binding and antioxidant capacity, is able to reduce the damage caused by metal ions and oxidative stress on nerve cells [7,8]. In addition, as an antioxidant, it can protect normal cells from external damage and reduce the risk of cancer [9].
What is an example of a metallothionein?
Metallothioneins have diverse metal-binding preferences, which have been associated with functional specificity. As an example, the mammalian Mus musculus MT1 preferentially binds divalent metal ions (Zn(II), Cd(II),...), while yeast CUP1 is selective for monovalent metal ions (Cu(I), Ag(I),...).
Where is metallothionein found?
Metallothioneins are small proteins that bind to heavy metals such as cadmium, zinc, and copper. They are rich in sulfhydryl groups and can be found in various tissues, including the liver, kidney, and intestine.
The meaning of METALLOTHIONEIN is any of various metal-binding proteins involved in the metabolism of copper and zinc in body tissue (as of the liver) and ...
Metallothioneins and phytochelatins are Cys-rich metal chelators that represent the two principal groups of metal-binding proteins found across most taxonomic ...
28/07/2009 · Definition of metallothionein: Protein involved in cell detoxification mechanisms for various heavy metals. This is the common definition for ...
Metallothionein is a small, cysteine-rich protein that binds to metals, such as cadmium, and is found in various organisms including animals, plants, ...
Metallothioneins (MTs) are a group of intracellular metal-binding and cysteine-enriched proteins and are highly inducible in many tissues in response to ...
25/06/2024 · In many types of cancer, metallothioneins are found to be overexpressed, contributing to the resistance of cancer cells to chemotherapy and ...
20/09/2017 · Metallothioneins are a family of proteins which are able to bind metals intracellularly, so their main function is to regulate the cellular ...
Previous studies have revealed that metallothionein (MT) can protect cells from apoptosis induced by oxidative stress and metals.
Metallothionein is the body's primary protection against heavy metals, a magnet for mercury, lead and cadmium. Intestinal MT prevents absorption of ingested ...
